Discovering & controlling protein function
through chemical genetics
Genomics has given us a parts list of the human cell, but we still don't understand how all the parts work together. Proteins rarely act alone: their interactions control gene regulation, signaling, and cellular state.
How can we uncover these interactions—and learn to rewire them?
We develop and combine chemical and genetic approaches to discover how proteins function, reveal unexpected molecular interactions, and create new opportunities for therapeutics.
Our lab brings together scientists from chemical biology, molecular biology, organic synthesis, biochemistry, and functional genomics. Together, we develop new approaches and tackle fundamental questions at the interface of chemistry and biology.
Our team
Recent news
2026
October
The lab welcomes Dr. Chrysanthi Kagiou to the lab!
Congratulations to Chao, Karl and the LSD1-GFI1B team and to Emma, Liv, and the DNMT3A team on having their papers accepted in principle at ACS Central Science and Nature Chemical Biology!
August
Congrats to our PI Brian for receiving the 2027 Tetrahedron Young Investigator Award For Bioorganic and Medicinal Chemistry.
July
Congrats to Simon on defending his Ph.D. and a big thanks to him and his amazing contributions throughout his years in the lab!
June
Congrats Ji, Simon, and Arjun for receiving the Blavatnik Biomedical Accelerator Grant!
Our lab is overjoyed to announce that our beloved Brian Liau will be awarded with tenure! Thank you to everyone who’s hard work and dedication made this happen, and our lab is only just getting started. We are proud of you Brian!
April
Congratulations to Camille for receiving the NSF GRF!
March
Congratulations to Simon for receiving a Harvard collaborative grant in conjunction with the Woo Lab!
January
A lot of changes in our lab. First, the lab welcomes two first-year graduate students, Arjun Garapaty and Camille Freedman! We’re excited to have them as part of our team. Second, late last year, we bid farewell to Dr. Hui Si Kwok and Dr. Emma Garcia and wish them all the best with their next academic steps. We will also miss Dr. Megan Yeo as she starts her new position in Amgen.
